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      當前位置:首頁 > 技術文章 > HMGBIOTECH DISULFIDE HMGB1說明書

      HMGBIOTECH DISULFIDE HMGB1說明書

      更新時間:2024-03-15      點擊次數:1733

      HMGBIOTECH   高遷移率蛋白、質粒、抗體


      hmgbiotech HM-120

      HMGB 1是細胞核的一個組成部分,在基因組的組織和表達中具有多種功能。HMG生物技術SRL為活躍在這一領域的其他研究人員和公司提供試劑、服務和想法。它還有助于實驗室開發分析和試劑。


      hmgbiotech  DISULFIDE HMGB1說明書


      hmgbiotech HM-120


      HMGB1是一種核蛋白,其由壞死細胞被動釋放,由凋亡細胞保留,并由炎癥細胞主動分泌(Dumitriu等人,HMGB1:從內部引導免疫。Trends Immunol 2005,26:381-7)。HMGB1對生命至關重要:HMGB1基因敲除小鼠出生后不久死亡。

      HMGB1作為運動細胞的化學引誘劑和細胞因子的誘導劑的兩種不同活性被歸因于不同的生物化學形式。還原的HMGB1(具有化學引誘活性的形式)被還原;二硫化物HMGB1包含C23和C45之間的二硫鍵(完整注釋:HMGB1C23-C45C106h–Antoine J.等人(2014)。Mol-Med)。

      二硫化物HMGB1可誘導單核細胞和其他炎癥細胞產生細胞因子和趨化因子(Venereau等人,2012)。

      在結構上,二硫化物HMGB1在半胱氨酸殘基23和45與還原的半胱氨酸殘基106之間具有二硫鍵。測試二硫化物HMGB1刺激細胞因子的能力




      HMGBiotech公司熱銷產品

      產品名稱

      貨號

      100 ug Fully reduced HMGB1, LPS free

      HM-115

      50 ug Fully reduced HMGB1, LPS free

      HM-116

      100 ug Disulfide HMGB1, LPS free

      HM-121

      100 ug BoxA from HMGB1, LPS-free and tested in migration assay

      HM-012

      50 ug Disulfide HMGB1, LPS free

      HM-122

      500 ug BoxA from HMGB1, LPS-free and tested in migration assay

      HM-013

      1 mg HMGB1 for biochemistry

      HM-100

      2.5 mg BoxA from HMGB1, LPS-free and tested in migration assay

      HM-014

      250 ug HMGB1 biochemistry

      HM-101

      25 ug BoxA from HMGB1, LPS-free and tested in migration assay

      HM-011

      15 ug BoxB from HMGB1, LPS-free and tested in migration assay

      HM-053

      15 ug Fully reduced HMGB1, LPS free

      HM-117

      10 ug Disulfide HMGB1, LPS free

      HM-123

      15 ug Non-oxidizable HMGB1, LPS free

      HM-133

      250 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration

      HM-170

      100 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration

      HM-171

      50 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration

      HM-172

      15 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration

      HM-173

      50 ug HMGB1 15N labelled for Mass Spectrometry

      HM-180

      5 ug HMGB1 15N labelled for Mass Spectrometry

      HM-181

      2.5 mg BoxA 2D from HMGB1, LPS-free and tested in migration assay

      HM-190

      500 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay

      HM-191

      100 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay

      HM-192

      25 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay

      HM-193

      Control cell lysates from Hmgb1 +/+

      HM-001

      Control cell lysates from Hmgb1 -/-

      HM-002

      1 mg BoxB from HMGB1, LPS-free and tested in migration assay

      HM-050

      250 ug BoxB from HMGB1, LPS-free and tested in migration assay

      HM-051

      100 ug BoxB from HMGB1, LPS-free and tested in migration assay

      HM-052

      500 ug Fully reduced HMGB1, LPS free

      HM-114

      250 ug Disulfide HMGB1, LPS free

      HM-120

      500 ug Non-oxidizable HMGB1, LPS free

      HM-130

      100 ug Non-oxidizable HMGB1, LPS free

      HM-131

      50 ug Non-oxidizable HMGB1, LPS free

      HM-132

      500 ug HMGB2, LPS-free and tested in migration assay

      HM-151

      100 ug HMGB2, LPS-free and tested in migration assay

      HM-152

      50 ug HMGB2, LPS-free and tested in migration assay

      HM-153

      Embryonic fibroblasts immortalized with large T antigen. One vial of -/- cells and one vial of +/+ cells

      HM-201

      Embryonic fibroblasts immortalized with the 3T3 method. One vial of -/- cells and one vial of +/+ cells

      HM-221

      Embryonic fibroblasts, Hmgb1-/- and HMGB2-low, immortalized with the 3T3 method. One vial of cells, and

      HM-223

      HMGB1 Isoforms Kit - Test size

      HM-030

      Embryonic fibroblasts immortalized with the 3T3 method. One vial of Hmgb2-/- cells and one vial of +/+ cells

      HM-251

      HMGB1 Isoforms Kit - Regular size

      HM-031

      20 ug p-mHMG1

      HM-300

      50 ug Terminally oxidized HMGB1, LPS free

      HM-062

      20 ug p-mHMG1tag

      HM-301

      100 ug Terminally oxidized HMGB1, LPS free

      HM-061

      20 ug pEGFP-HMGB1

      HM-302

      250 ug Terminally oxidized HMGB1, LPS free

      HM-060

      20 ug pcDNA/FL-RAGE plasmid

      HM-310



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